Publication Abstract

Title: Plasma levels of sex steroids, including 17alpha, 20alpha-dihydroxy-4-pregnen-3-one and 3beta, 17alpha, 20alpha-trihydroxy-5beta-pregnene, in female dabs, Limanda limanda, induced to mature and ovulate with human chorionic gonadotrophin

Publication Abstract: Plasma levels of sex steroids, including 1alpha, 20alpha-dihydroxy-4-pregnen-3-one and 3beta, 1alpha, 20alpha-trihydroxy-5beta-pregnene, in female dabs, Limanda limanda, induced to mature and ovulate with human chorionic gonadotrophin

A.V.M. Canario and A.P. Scott

Human chorionic gonadotropin (HCG) effectively stimulated oocyte final maturation and ovulation in female dabs (Limanda limanda) within 5 days of injection, and this was accompanied by significant changes in blood plasma steroid levels. The steroids which showed the greatest responses to the HCG injections were the ones previously found to be the major products of the ovaries in vitro: 17alpha, 20alpha-dihydroxy-4-pregnen-3-one (17,20alpha -P) and 3 beta, 17alpha, 20 alpha -trihydroxy-5 beta -pregnane (3 beta,17,20 alpha -P-5 beta ). Of the other C₂₁ steroids identified in the ovaries of teleosts, 17alpha, 20beta -21-trihydroxy-4-pregnen-3-one could not be detected, and 17alpha, 21-dihydroxy-4-pregnene-3,20-dione (11-deoxycortisol) showed nonsignificant changes compared to the saline-injected controls. HCG caused a decrease in estradiol-17 beta levels within 24 hr, but levels then rose again to a maximum of 8.2 ng ml ^-1 at ovulation time, possibly caused by the presence of vitellogenic oocytes in the ovaries. Changes in testosterone levels, however, were not significantly different between HCG- and saline-injected females.

Reference:

A.V.M. Canario and A.P. Scott, 1990. Plasma levels of sex steroids, including 1alpha, 20alpha-dihydroxy-4-pregnen-3-one and 3beta, 1alpha, 20alpha-trihydroxy-5beta- pregnene, in female dabs, Limanda limanda, induced to mature and ovulate with human chorionic gonadotrophin. General and Comparative Endocrinology, 77: 177-191.

Publication Internet Address of the Data

Publication Authors: A.V.M. Canario* and A.P. Scott*

Publication Date: January 1990

Publication Reference: General and Comparative Endocrinology, 77: 177-191

Publication DOI: https://doi.org/

Publication Abstract

Plasma levels of sex steroids, including 1alpha, 20alpha-dihydroxy-4-pregnen-3-one and 3beta, 1alpha, 20alpha-trihydroxy-5beta-pregnene, in female dabs, Limanda limanda, induced to mature and ovulate with human chorionic gonadotrophin

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