Publication Abstract
- Title
-
Molecular comparison of isolates of an emerging fish pathogen, koi herpesvirus, and the effect of water temperature on mortality of experimentally infected koi
- Publication Abstract
-
Molecular comparison of isolates of an emerging fish pathogen, koi herpesvirus, and the effect of water temperature on mortality of experimentally infected koi
O. Gilad, S. Yun, M.A. Adkison, K. Way *, N.H. Willits, H. Bercovier and R.P. Hedrick
The koi herpesvirus (KHV) has been associated with devastating losses of both common carp (Cyprinus carpio carpio) and koi (Cyprinus carpio koi) in North America, Europe, Israel and Asia. A comparison of the virion polypeptides and genomic restriction fragments of 7 geographically diverse isolates of KHV indicated that all but one isolate represented a homogeneous group. A principal environmental factor influencing disease is water temperature. Optimal growth of KHV in the koi fin (KF-1) cell line occurred at temperatures from 15 - 25oC. There was no or minimal growth at 4, 10, 30 or 37oC. Experimental infections of koi with KHV at a water temperature of 23°C resulted in a 95.2% cumulative mortality. Disease progressed rapidly but with less mortality (95.2 - 89.4%) at 28°C. Mortality (85.0%) also occurred at 18°C but not at 13°C. Shifting virus-exposed fish from 13°C to 23°C resulted in a rapid onset of mortality.
Reference:
O. Gilad, S. Yun, M.A. Adkison, K. Way, N.H. Willits, H. Bercovier and R.P. Hedrick, 2003. Molecular comparison of isolates of an emerging fish pathogen, koi herpesvirus, and the effect of water temperature on mortality of experimentally infected koi. Journal of General Virology, 84(10): 2661-2668.
- Publication Internet Address of the Data
- Publication Authors
-
O. Gilad, S. Yun, M.A. Adkison, K. Way *, N.H. Willits, H. Bercovier and R.P. Hedrick
- Publication Date
- November 2003
- Publication Reference
-
Journal of General Virology, 84(10): 2661-2668
- Publication DOI: https://doi.org/
