Publication Abstract
- Title
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The stable aryl hydrocarbon receptor agonist potency of United Kingdom Continental Shelf (UKCS) offshore produced water effluents
- Publication Abstract
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The stable aryl hydrocarbon receptor agonist potency of United Kingdom Continental Shelf (UKCS) offshore produced water effluents
M.R. Hurst, Y.L. Chan-Man, J. Balaam, J. E. Thain and K.V. Thomas
The in vitro aryl hydrocarbon receptor (AhR) agonist potency of offshore produced water effluents collected from the UK Continental shelf was determined using the dioxin responsive (DR)- Chemically Activated Luciferase Expression (CALUX) assay. Octadecylsilane (C18) solid phase extraction (SPE) extracts of produced water were exposed to DR-CALUX cells for 24 h in order to investigate the potency of ofcompounds that are stable to metabolism by the CALUX cells during exposure. The stable AhR agonist potency determined in the extracts was highly variable and ranged from 1 to 430 ng TCDD TEQ CALUX l-1. These data reflect the varying composition of produced water discharges from different production fields. It is recommended that further work be performed to characterise the full range of stable dioxin like AhR agonists present in offshore produced water discharges using techniques such as bioassay-directed analysis.
Reference:
M.R. Hurst, Y.L. Chan-Man, J. Balaam, J. E. Thain and K.V. Thomas (2004) The stable aryl hydrocarbon receptor agonist potency of United Kingdom Continental Shelf (UKCS) offshore produced water effluents. Marine Pollution Bulletin, 50: 1694-1698
- Publication Internet Address of the Data
- Publication Authors
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M.R. Hurst*, Y.L. Chan-Man*, J. Balaam*, J. E. Thain* and K.V. Thomas*
- Publication Date
- December 2005
- Publication Reference
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Marine Pollution Bulletin, 50: 1694-1698
- Publication DOI: https://doi.org/
