Publication Abstract

The reproductive behaviour of the three-spined stickleback as a novel assay for the detection of anti-androgens

Marion Sebire* and Ioanna Katsiadaki*

An anti-androgen assay was developed using spiggin levels and reproductive behaviour in the male three-pined stickleback, Gasterosteus aculeatus, as endpoints. Here we present the results using flutamide (FL) and fenitrothion (FN), two compounds with anti-androgenic properties. Reduction in both spiggin levels and in number of nests was observed with increasing concentrations of the chemicals, suggesting a significant adverse effect of anti-androgens on the biology of the stickleback.

Reference

Marion Sebire* and Ioanna Katsiadaki*  (2008) The reproductive behaviour of the three-spined stickleback as a novel assay for the detection of anti-androgens. CYBIUM, International Journal of Ichthyology 32(2) suppl; 59-60